![Thursday Night Football: 49ers open as double-digit favorites vs](https://www.usatoday.com/gcdn/authoring/authoring-images/2023/09/22/USAT/70927469007-usatsi-21473678.jpg?crop=3146,1769,x171,y225)
49ers-Giants highlights: Thursday Night Football score, top plays
![Thursday Night Football: 49ers open as double-digit favorites vs](https://www.pointspreads.com/wp-content/uploads/2023/10/broncos-vs-chiefs-betting-preview-chiefs-a-double-digit-favorite-on-tnf.webp)
Broncos vs Chiefs Betting Preview: Can KC Stay Dominant?
![Thursday Night Football: 49ers open as double-digit favorites vs](https://cdn.vegasinsider.com/wp-content/BPurdyWk4WP.jpg)
NFL Odds Week 4: Cardinals vs 49ers Lines, Spreads, Betting Trends
![Thursday Night Football: 49ers open as double-digit favorites vs](https://a.espncdn.com/photo/2022/1103/r1085362_1296x729_16-9.jpg)
NFL Week 9 betting notes - Underwhelming history for overwhelming
![Thursday Night Football: 49ers open as double-digit favorites vs](https://sports.betmgm.com/en/blog/wp-content/uploads/2023/09/nfl-mahomes-chiefs-betmgm-1.jpg)
NFL Odds Week 3: Biggest NFL Spreads This Week
![Thursday Night Football: 49ers open as double-digit favorites vs](https://www.bettingodds.com/media/images/admin/betting-odds-us/0921.giants49erspickspredictions.jpg)
New York Giants vs. San Francisco 49ers: Week 3 Predictions, Picks
![Thursday Night Football: 49ers open as double-digit favorites vs](https://www.oregonlive.com/resizer/priYf0njoptVllJGJalFZ0K7bRw=/1280x0/smart/cloudfront-us-east-1.images.arcpublishing.com/advancelocal/FXU65GHQVZEUNCD3RRCZKZDKOE.jpg)
Bet365 Ohio Bonus Code ORLIVEOH: Bet $1, Claim $365 in Bonus bets
![Thursday Night Football: 49ers open as double-digit favorites vs](https://i.ytimg.com/vi/jeoGbxgmrSs/hqdefault.jpg)
49ers vs Rams Odds, Picks & Predictions - NFL Week 2
![Thursday Night Football: 49ers open as double-digit favorites vs](https://www.inquirer.com/resizer/btEef_yjmws4YRom--Z8jYmPHz4=/arc-anglerfish-arc2-prod-pmn/public/IPPKBEGA7FBHRO4RGBU7XKZB4M.jpg)
NFL week 3 odds: Eagles road favorites against Bucs in Monday